1 00:00:07,349 --> 00:00:05,190 whether it's losing weight or just 2 00:00:09,190 --> 00:00:07,359 making better choices we all get that 3 00:00:11,589 --> 00:00:09,200 first of the year boost when it comes to 4 00:00:13,110 --> 00:00:11,599 nutrition and getting healthy but for 5 00:00:15,509 --> 00:00:13,120 astronauts on the international space 6 00:00:17,189 --> 00:00:15,519 station it's a daily routine they have 7 00:00:19,349 --> 00:00:17,199 to think about everything they eat and 8 00:00:21,750 --> 00:00:19,359 how it will affect their overall health 9 00:00:23,029 --> 00:00:21,760 so we study nutrition in space and the 10 00:00:24,790 --> 00:00:23,039 things we're learning from these 11 00:00:27,109 --> 00:00:24,800 astronaut studies are shedding light on 12 00:00:29,589 --> 00:00:27,119 problems we face here on earth such as 13 00:00:31,349 --> 00:00:29,599 vision bone loss and vitamin d 14 00:00:34,150 --> 00:00:31,359 deficiencies what we're doing is trying 15 00:00:35,750 --> 00:00:34,160 to evaluate nutrition and basic 16 00:00:37,350 --> 00:00:35,760 physiology if you will 17 00:00:38,389 --> 00:00:37,360 in astronauts while they're on space 18 00:00:41,030 --> 00:00:38,399 station 19 00:00:42,229 --> 00:00:41,040 and it's very similar to 20 00:00:43,830 --> 00:00:42,239 when you go to the doctor and you get a 21 00:00:45,270 --> 00:00:43,840 checkup 22 00:00:47,190 --> 00:00:45,280 they'll draw a blood sample they'll 23 00:00:48,709 --> 00:00:47,200 collect the urine sample 24 00:00:50,150 --> 00:00:48,719 and we'll look at things in there to see 25 00:00:51,590 --> 00:00:50,160 how you're doing 26 00:00:54,150 --> 00:00:51,600 that's in essence what we're doing with 27 00:00:56,470 --> 00:00:54,160 it with a cruise we collect blood and 28 00:00:57,990 --> 00:00:56,480 urine samples during space flight 29 00:01:00,470 --> 00:00:58,000 over the course of a six-month mission 30 00:01:02,069 --> 00:01:00,480 we collect five blood samples and five 31 00:01:03,349 --> 00:01:02,079 urine samples 32 00:01:05,590 --> 00:01:03,359 and we measure 33 00:01:06,789 --> 00:01:05,600 a whole host of things in those samples 34 00:01:09,190 --> 00:01:06,799 to look at 35 00:01:10,950 --> 00:01:09,200 vitamin status and mineral status 36 00:01:13,109 --> 00:01:10,960 we look at things like bone metabolism 37 00:01:15,030 --> 00:01:13,119 we look at some muscle markers some 38 00:01:16,789 --> 00:01:15,040 oxidative damage markers 39 00:01:18,149 --> 00:01:16,799 you name it there's a lot of a lot of 40 00:01:20,550 --> 00:01:18,159 biochemistry in that blood urine that 41 00:01:23,270 --> 00:01:20,560 can tell us how your body's doing 42 00:01:24,710 --> 00:01:23,280 in our case during space flight 43 00:01:26,789 --> 00:01:24,720 we're looking at different chemicals 44 00:01:28,469 --> 00:01:26,799 that 45 00:01:30,870 --> 00:01:28,479 have helped us better understand some of 46 00:01:32,149 --> 00:01:30,880 the the medical issues that occur during 47 00:01:34,230 --> 00:01:32,159 spaceflight 48 00:01:35,510 --> 00:01:34,240 and the most significant one of those is 49 00:01:36,950 --> 00:01:35,520 we found 50 00:01:38,789 --> 00:01:36,960 crew members coming back from space 51 00:01:41,429 --> 00:01:38,799 station with vision problems 52 00:01:44,230 --> 00:01:41,439 crew members that went up with perfect 53 00:01:47,510 --> 00:01:44,240 vision and came home needing glasses 54 00:01:50,230 --> 00:01:47,520 in the in its simplest explanation and 55 00:01:53,190 --> 00:01:50,240 what we found in data from uh blood 56 00:01:56,310 --> 00:01:53,200 samples is that there are differences in 57 00:01:57,830 --> 00:01:56,320 the biochemical profiles of crew members 58 00:01:59,270 --> 00:01:57,840 that had vision issues compared to those 59 00:02:00,870 --> 00:01:59,280 that did not 60 00:02:02,950 --> 00:02:00,880 and were working to follow up on that to 61 00:02:05,030 --> 00:02:02,960 try to help better understand 62 00:02:07,429 --> 00:02:05,040 the vision changes during flight 63 00:02:10,469 --> 00:02:07,439 the research they were doing in flight 64 00:02:12,710 --> 00:02:10,479 from from two perspectives um has a lot 65 00:02:15,430 --> 00:02:12,720 to do with people on earth 66 00:02:17,990 --> 00:02:15,440 just understanding basic physiology uh 67 00:02:19,990 --> 00:02:18,000 basic nutritional requirements um can 68 00:02:22,630 --> 00:02:20,000 help us better understand 69 00:02:23,990 --> 00:02:22,640 those same things on earth the bone loss 70 00:02:26,150 --> 00:02:24,000 that we see during space flight is very 71 00:02:27,910 --> 00:02:26,160 similar to some bone diseases that 72 00:02:29,589 --> 00:02:27,920 people on earth get 73 00:02:32,070 --> 00:02:29,599 and we're studying them in a very 74 00:02:34,309 --> 00:02:32,080 healthy population so 75 00:02:36,229 --> 00:02:34,319 that helps us better understand 76 00:02:38,630 --> 00:02:36,239 the nature of those diseases and then on 77 00:02:40,869 --> 00:02:38,640 the other hand as we develop means to 78 00:02:43,270 --> 00:02:40,879 help counteract those diseases or those 79 00:02:45,830 --> 00:02:43,280 issues during space flight 80 00:02:48,150 --> 00:02:45,840 those two have direct application uh for 81 00:02:50,150 --> 00:02:48,160 people on earth be it dietary changes 82 00:02:51,350 --> 00:02:50,160 that can help mitigate bone loss during 83 00:02:52,790 --> 00:02:51,360 flight 84 00:02:54,150 --> 00:02:52,800 one of the things is that you know we 85 00:02:55,830 --> 00:02:54,160 did some studies 86 00:02:57,509 --> 00:02:55,840 to help better understand how much 87 00:02:58,390 --> 00:02:57,519 vitamin d people needed during space 88 00:03:00,550 --> 00:02:58,400 flight 89 00:03:02,710 --> 00:03:00,560 and we've now got a point where where 90 00:03:05,110 --> 00:03:02,720 we're maintaining vitamin d levels in 91 00:03:07,830 --> 00:03:05,120 our astronauts those data were actually 92 00:03:10,070 --> 00:03:07,840 incorporated in the group the the 93 00:03:12,149 --> 00:03:10,080 institute of medicine who sets the 94 00:03:14,470 --> 00:03:12,159 recommended dietary allowances the rdas 95 00:03:16,869 --> 00:03:14,480 for the population 96 00:03:18,710 --> 00:03:16,879 our study was one of the many studies 97 00:03:20,149 --> 00:03:18,720 that those groups looked at to help 98 00:03:21,750 --> 00:03:20,159 better understand 99 00:03:22,869 --> 00:03:21,760 vitamin d requirements for people on 100 00:03:24,470 --> 00:03:22,879 earth so 101 00:03:25,509 --> 00:03:24,480 there's a there's a lot of interaction 102 00:03:26,390 --> 00:03:25,519 but again 103 00:03:32,390 --> 00:03:26,400 um 104 00:03:34,789 --> 00:03:32,400 it it overlaps 105 00:03:37,190 --> 00:03:34,799 entirely we still have a lot of work to 106 00:03:39,670 --> 00:03:37,200 do based on the many findings that we've 107 00:03:41,350 --> 00:03:39,680 gotten out of our first nutrition study 108 00:03:42,550 --> 00:03:41,360 we've actually evolved that into a 109 00:03:45,430 --> 00:03:42,560 follow-on study what we're calling the 110 00:03:47,670 --> 00:03:45,440 biochemical profile experiment where 111 00:03:49,589 --> 00:03:47,680 again we're collecting 112 00:03:51,589 --> 00:03:49,599 blood and urine samples to look at the 113 00:03:53,910 --> 00:03:51,599 adaptation of space flight 114 00:03:54,789 --> 00:03:53,920 we're also starting up 115 00:03:56,229 --> 00:03:54,799 some 116 00:03:58,229 --> 00:03:56,239 what we call the integrated nutrition 117 00:03:59,910 --> 00:03:58,239 study where we're looking to modify 118 00:04:02,390 --> 00:03:59,920 people's diets to provide healthier 119 00:04:04,390 --> 00:04:02,400 diets to see if we can use those as ways 120 00:04:06,309 --> 00:04:04,400 to mitigate some of the negative effects 121 00:04:08,229 --> 00:04:06,319 of space flight on the human body 122 00:04:09,509 --> 00:04:08,239 and those are in the very early stages 123 00:04:10,869 --> 00:04:09,519 but hopefully 124 00:04:12,309 --> 00:04:10,879 in a few years i'll be back talking